General Healthcare, Health

Over-the-Counter Medications and Supplements That Can Be Risky for Older Adults


For older adults, particularly those over 50, certain over-the-counter (OTC) medications and dietary supplements can pose increased risks due to changes in metabolism, potential drug interactions, and age-related health conditions. Here’s a breakdown of some common medications and supplements, their associated risks, and suggestions for safe usage:

1. NSAIDs (Ibuprofen – Advil, Motrin; Naproxen – Aleve)

  • Risks: NSAIDs can increase the risk of stomach ulcers, gastrointestinal bleeding, kidney damage, and elevate blood pressure. Long-term use in older adults can worsen cardiovascular health.
  • Suggestions: Limit use to the lowest effective dose for the shortest duration. Consider using acetaminophen for pain relief instead of NSAIDs, as it has fewer gastrointestinal risks. Speak to a doctor if regular use is needed.

2. Acetaminophen (Tylenol)

  • Risks: Acetaminophen is generally safe, but it can lead to liver damage if taken in doses exceeding 3,000 mg per day, especially when combined with alcohol or in individuals with pre-existing liver issues.
  • Suggestions: Monitor total daily intake, especially if taking other medications like cold or flu remedies that also contain acetaminophen.

3. Aspirin

  • Risks: Aspirin increases the risk of gastrointestinal bleeding and should be used cautiously by older adults, especially in combination with other blood thinners. It is also linked to a higher risk of bleeding in the brain.
  • Suggestions: Use aspirin under medical guidance, particularly for those with cardiovascular issues, and monitor for any signs of bleeding (e.g., dark stools).

4. Antihistamines (Benadryl – Diphenhydramine)

  • Risks: First-generation antihistamines like Benadryl can cause drowsiness, confusion, dry mouth, and urinary retention. They can increase the risk of falls and worsen dementia symptoms.
  • Suggestions: Avoid long-term use. Consider second-generation antihistamines (like loratadine or cetirizine) as they have fewer sedating effects.

5. Decongestants (Pseudoephedrine, Phenylephrine)

  • Risks: These can raise blood pressure, cause insomnia, and worsen heart conditions. They are risky for people with hypertension or cardiovascular diseases.
  • Suggestions: Consult a doctor before use, especially if you have a history of high blood pressure. Nasal sprays like saline can offer safer alternatives for congestion.

6. Flonase (Fluticasone), Rhinocort (Budesonide)

  • Risks: Nasal corticosteroids are generally safe but can cause nosebleeds or irritation with long-term use. In rare cases, they might contribute to bone thinning.
  • Suggestions: Use as directed and avoid overuse. If nosebleeds or irritation occur, speak with a healthcare provider.

7. Proton Pump Inhibitors (PPIs) – Prilosec (Omeprazole), Nexium (Esomeprazole), Prevacid (Lansoprazole)

  • Risks: Long-term use of PPIs may lead to nutrient deficiencies (e.g., magnesium, calcium), increased risk of fractures, and kidney problems. There is also evidence linking PPIs to infections like C. difficile.
  • Suggestions: Use PPIs for the shortest duration necessary. For chronic use, consult with a doctor about regular monitoring for nutrient levels and kidney function.

8. Laxatives (Magnesium Citrate, Milk of Magnesia)

  • Risks: Overuse can lead to electrolyte imbalances, dehydration, and dependence on laxatives for bowel movements.
  • Suggestions: Use laxatives sparingly and focus on dietary solutions like increased fiber and water intake. Consult a healthcare provider if constipation persists.

9. Oxybutynin (Oxytrol for Women)

  • Risks: Oxybutynin can cause dry mouth, dizziness, and confusion, especially in older adults. It may also increase the risk of urinary retention.
  • Suggestions: Use only under medical supervision, particularly if other medications that affect the nervous system are involved.

10. Dietary Supplements (Ginkgo, Ginseng, Garlic, Valerian, Kava)

  • Risks:
    • Ginkgo & Garlic: Both may increase the risk of bleeding, especially if combined with blood thinners.
    • Ginseng: Can interfere with blood sugar control and increase bleeding risk.
    • Valerian & Kava: Linked to liver damage when taken long-term or in high doses. These can also interact with sedatives, increasing the risk of excessive drowsiness or confusion.
  • Suggestions: Always consult with a healthcare provider before starting any supplements, particularly if you’re taking prescription medications or have pre-existing conditions.

General Tips for Safe Medication Use in Older Adults:

  1. Consult a Healthcare Provider: Before starting any new medication or supplement, it’s crucial to discuss it with a healthcare provider who knows your medical history.
  2. Be Aware of Drug Interactions: Many OTC medications and supplements can interact with prescription medications, leading to harmful effects.
  3. Read Labels Carefully: Always check labels for potential side effects, dosage recommendations, and interactions with other medications or health conditions.
  4. Use Medications Only When Needed: Avoid long-term use of OTC medications unless advised by a healthcare professional. If symptoms persist, seek medical advice.
  5. Monitor for Side Effects: Be vigilant about any changes in how you feel after starting a new medication or supplement, and report adverse effects to a healthcare provider.

-Thanh Thuỷ-

Sources for Further Reading:

  • National Institute on AgingSafe Use of Medicines for Older Adults
  • FDA – OTC Medication Safety
  • American Geriatrics Society – Beers Criteria for Potentially Inappropriate Medication Use in Older Adults

These sources provide comprehensive guidelines on the risks of medications and supplements in older adults and can help inform safer practices.